By J.K. Aronson (Eds.)

ISBN-10: 0444532943

ISBN-13: 9780444532947

The unintended effects of substances Annual was once first released in 1977. it's been continuously released seeing that then, as a each year replace to the voluminous encyclopedia Meyler's negative effects of substances. every one new Annual keeps to supply clinicians and scientific investigators with a competent and demanding each year survey of latest information and traits within the region of difficult Drug Reactions and Interactions. a world staff of experts has contributed to the informative, via seriously studying it, and by means of pointing to no matter what is deceptive. *Provides a serious each year survey of latest information and developments *Special reports during this Annual comprise, between different themes: Epidemiology of using ecstasy, Paracetamol and the chance of bronchial asthma, mix vaccines/multiple immunizations, Interactions of natural medicinal drugs with warfarin, and Tyrosine kinase inhibitors.

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Extra info for A worldwide yearly survey of new data and trends in adverse drug reactions

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Drug Inf J 1995;29 (4):1133–43. 5. Brown EG, Clark E. Evaluation of MedDRA in representing medicinal product data 6. 7. 8. 9. sheet information. Pharmac Med 1996;10:111–8. Tonéatti C, Saïdi Y, Meiffrédy V, Tangre P, Harel M, Eliette V, Dormont J, Pierre Aboulker J. Experience using MedDRA for global events coding in HIV clinical trials. Contemp Clin Trials 2006;27:13–22. Harrison J, Zhao-Wong A. Working with MedDRA to improve data standards. Good Clin Pract J 2006;13(9):25–8. 10, 1 April 2008. pdf.

Ecstasy (3,4-methylenedioxymetamfetamine, MDMA) See Chapter 4. Metamfetamine (SEDA-29, 3; SEDA-30, 2) Cardiovascular Patients with idiopathic pulmonary arterial hypertension (PAH) are significantly more likely to have used stimulants than patients with other forms of pulmonary hypertension. In a retrospective study, rates of stimulant use were determined in 340 patients with idiopathic PAH, PAH with known susceptibility factors, or chronic thromboembolic pulmonary hypertension. “Stimulant” use was defined as any self-reported use of amfetamine, metamfetamine, or cocaine (4C).

Once in this “production” phase, MedDRA subscri­ bers are free to recommend changes to SMQs in a similar change request process as used for the main MedDRA terminol­ ogy (12). 1, there are 67 SMQs in production, and about a dozen additional ones in the develop­ ment and testing phases. The available queries cover a wide variety of important areas in clinical safety and post-market­ ing pharmacovigilance. Topics include: � � � � � � � anaphylactic reactions; cerebrovascular disorders; depression and suicide/self-injury; hepatic disorders; lack of efficacy/effect; rhabdomyolysis/myopathy; torsade de pointes/QT interval prolongation.

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A worldwide yearly survey of new data and trends in adverse drug reactions by J.K. Aronson (Eds.)


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